Abstract : The impact of HIV/AIDS on households was assessed by means of a longitudinal (cohort) study of households affected by the disease. The CHSR D established a formal relationship with various stakeholders in the two study sites to facilitate the recruitment of affected households. Verbal informed consent was obtained from infected individuals to interview the households to which they belong. The household impact of HIV/AIDS was determined by comparing over time the observed trends in health outcomes and socioeconomic variables in HIV/AIDS-affected households and a control group using statistical methods. For this purpose, a survey on the quality of life and the economics of affected and non-affected households was conducted. The results reported in this report are based on the analysis of data from two panels of interviews conducted with a total of 387 households.